Nafis A Rahman Selected Research

hecate-chorionic gonadotropin beta-subunit conjugate

6/2009	Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter.
6/2008	Targeted therapy for adrenocortical tumors in transgenic mice through their LH receptor by Hecate-human chorionic gonadotropin beta conjugate.
5/2005	A novel targeted therapy of Leydig and granulosa cell tumors through the luteinizing hormone receptor using a hecate-chorionic gonadotropin beta conjugate in transgenic mice.
4/2004	Growth repression in diethylstilbestrol/dimethylbenz[a]anthracene-induced rat mammary gland tumor using Hecate-CGbeta conjugate.

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Nafis A Rahman Research Topics

Disease

19	Neoplasms (Cancer) 01/2022 - 04/2004
4	Carcinogenesis 01/2017 - 10/2004
3	Ovarian Neoplasms (Ovarian Cancer) 09/2019 - 01/2012
3	Granulosa Cell Tumor 03/2014 - 05/2005
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 11/2015
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Leydig Cell Tumor 11/2020
1	Androgen-Insensitivity Syndrome (Testicular Feminization) 10/2019
1	Mastitis 10/2019
1	Ovarian Epithelial Carcinoma 09/2019
1	Adrenocortical Carcinoma 01/2019
1	Adenocarcinoma 01/2017
1	Adenoma (Adenomas) 01/2017
1	Hyperplasia 01/2017
1	Endometriosis 01/2016
1	Male Infertility (Male Sterility) 06/2014
1	Infertility (Sterility) 06/2014
1	Nonobstructive Azoospermia 06/2014
1	Inguinal Hernia (Direct Inguinal Hernia) 03/2011
1	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 03/2011
1	Carcinoma (Carcinomatosis) 04/2004

Drug/Important Bio-Agent (IBA)

9	Tumor Viral Antigens (Large T Antigen)IBA 01/2019 - 10/2004
9	LH Receptors (LH Receptor)IBA 03/2014 - 04/2004
7	GonadotropinsIBA 01/2021 - 04/2007
7	Inhibins (Inhibin)IBA 01/2019 - 04/2007
6	Luteinizing Hormone (Lutropin)FDA LinkGeneric 01/2021 - 05/2005
5	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 01/2019 - 04/2004
4	Peptides (Polypeptides)IBA 03/2014 - 04/2004
4	hecate-chorionic gonadotropin beta-subunit conjugateIBA 06/2009 - 04/2004
3	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2021 - 06/2009
3	Estrogens (Estrogen)FDA Link 01/2016 - 03/2011
3	Proteins (Proteins, Gene)FDA Link 01/2012 - 10/2004
3	inhibin-alpha subunitIBA 06/2008 - 10/2004
3	Messenger RNA (mRNA)IBA 06/2008 - 04/2004
2	Zona Pellucida GlycoproteinsIBA 01/2022 - 03/2014
2	Follicle Stimulating Hormone (Follitropin)FDA Link 01/2021 - 01/2019
2	AndrogensIBA 01/2021 - 10/2019
2	FSH Receptors (FSH Receptor)IBA 01/2021 - 01/2019
2	Mifepristone (RU 486)FDA Link 11/2020 - 09/2019
2	EnzymesIBA 10/2019 - 01/2017
2	Progesterone FDA LinkGeneric 09/2019 - 05/2005
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 06/2014
2	GATA4 Transcription FactorIBA 01/2017 - 10/2004
2	Estrogen ReceptorsIBA 01/2016 - 06/2014
2	Aromatase (CYP19)IBA 06/2014 - 03/2011
2	AcidsIBA 06/2008 - 04/2004
1	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 01/2021
1	SteroidsIBA 11/2020
1	Progesterone Receptors (Progesterone Receptor)IBA 11/2020
1	Androgen Receptors (Androgen Receptor)IBA 10/2019
1	LipopolysaccharidesIBA 10/2019
1	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)IBA 10/2019
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2019
1	cetrorelix (Cetrotide)FDA Link 01/2019
1	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 01/2017
1	Caspase 3 (Caspase-3)IBA 01/2017
1	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 01/2017
1	AntigensIBA 01/2017
1	Prostate-Specific Antigen (Semenogelase)IBA 11/2015
1	A-factor (Streptomyces)IBA 11/2015
1	Thymidine KinaseIBA 03/2014
1	Glycoproteins (Glycoprotein)IBA 01/2012
1	Ubiquitin CIBA 03/2011
1	Amino Acids FDA Link 06/2009
1	Estradiol (Delestrogen)FDA LinkGeneric 06/2009
1	Transcription Factors (Transcription Factor)IBA 04/2007
1	salicylhydroxamic acid (SHAM)IBA 04/2004
1	Diethylstilbestrol (Stilbestrol)FDA Link 04/2004
1	anthraceneIBA 04/2004

Therapy/Procedure

6	Therapeutics 01/2019 - 05/2005
4	Immunotherapy 01/2022 - 01/2012
4	Castration 01/2021 - 04/2013
1	Drug Therapy (Chemotherapy) 06/2008
1	Injections 04/2004